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1

Normalization of Low-Density Lipoprotein Receptor Expression in Receptor Defective Homozygous Familial Hypercholesterolemia by Inhibition of PCSK9 With Alirocumab

Lambert, Gilles, Chatelais, Mathias, Petrides, Francine, Passard, Maxime, Thedrez, Aurélie, Rye, Kerry-Anne, Schwahn, Uwe, Gusarova, Viktoria, Blom, Dirk J., Sasiela, William, Marais, A. David

Journal:

Journal of the American College of Cardiology

Year:

2014

Language:

english

File:

PDF, 233 KB

english, 2014

2

Alirocumab, a Fully Human Monoclonal Antibody to Proprotein Convertase Subtilisin/kexin Type 9: Therapeutic Dosing in Phase 3 Studies

Pordy, Robert, Lecorps, Guillaume, Bessac, Laurence, Sasiela, William J., Ginsberg, Henry

Journal:

Journal of Clinical Lipidology

Year:

2013

Language:

english

File:

PDF, 48 KB

english, 2013

3

IMPACT OF STATIN INTOLERANCE RATES ON NEED FOR EZETIMIBE AND/OR PCSK9 INHIBITORS FOR MEETING LOW-DENSITY LIPOPROTEIN GOALS IN A REAL-WORLD COHORT WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE

Cannon, Christopher P., Khan, Irfan, Klimchak, Alexa, Sanchez, Robert, Sasiela, William, Reynolds, Matthew

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 369 KB

english, 2017

4

Anticoagulation for the Treatment of Cancer-Associated Thrombosis: A Systematic Review and Network Meta-Analysis of Randomized Trials

Sobieraj, Diana M., Baker, William L., Smith, Eni, Sasiela, Katarzyna, Trexler, Stephanie E., Kim, Oliver, Coleman, Craig I.

Journal:

Clinical and Applied Thrombosis/Hemostasis

Year:

2018

Language:

english

File:

PDF, 281 KB

english, 2018

5

EFFECTS OF COOKING CONDITIONS AND POST-PREPARATION PROCEDURES ON THE QUALITY OF BATTERED FISH PORTIONS

GEORGE J. FLICK JR., YING-YING GWO, ROBERT L. ORY, WILLIAM L. BARAN, RONALD J. SASIELA, JOE BOLING, CAROLYN H. VINNETT, ROY E. MARTIN, GENARO C. ARGANOSA

Journal:

Journal of Food Quality

Year:

1989

Language:

english

File:

PDF, 673 KB

english, 1989

6

Safety of Very Low Low-Density Lipoprotein Cholesterol Levels With Alirocumab

Robinson, Jennifer G., Rosenson, Robert S., Farnier, Michel, Chaudhari, Umesh, Sasiela, William J., Merlet, Laurence, Miller, Kathryn, Kastelein, John J.P.

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.10 MB

english, 2017

7

A Randomized Study of the Relative Pharmacokinetics, Pharmacodynamics, and Safety of Alirocumab, a Fully Human Monoclonal Antibody to PCSK9, After Single Subcutaneous Administration at Three Different Injection Sites in Healthy Subjects

Lunven, Catherine, Paehler, Tobias, Poitiers, Franck, Brunet, Aurélie, Rey, Jacques, Hanotin, Corinne, Sasiela, William J.

Journal:

Cardiovascular Therapeutics

Year:

2014

Language:

english

File:

PDF, 246 KB

english, 2014

8

Plaque Stabilization: Can We Turn Theory into Evidence?

Peter Libby, William Sasiela

Journal:

The American Journal of Cardiology

Year:

2006

Language:

english

File:

PDF, 336 KB

english, 2006

9

Cellular Models of Atherosclerosis in the Young

STANLEY D. FOWLER, PERRY D. GASQUECARTER, ELIZABETH PATTILLO-ADKISSON, WILLIAM J. SASIELA, DAN N. XENACHIS

Journal:

Annals of the New York Academy of Sciences

Year:

1991

Language:

english

File:

PDF, 1.21 MB

english, 1991

10

Simulation of Lipid-Lowering Therapy Intensification in a Population With Atherosclerotic Cardiovascular Disease

Cannon, Christopher P., Khan, Irfan, Klimchak, Alexa C., Reynolds, Matthew R., Sanchez, Robert J., Sasiela, William J.

Journal:

JAMA Cardiology

Year:

2017

Language:

english

File:

PDF, 531 KB

english, 2017

11

Relationship Between Low‐Density Lipoprotein Cholesterol, Free Proprotein Convertase Subtilisin/Kexin Type 9, and Alirocumab Levels After Different Lipid‐Lowering Strategies

Rey, Jacques, Poitiers, Franck, Paehler, Tobias, Brunet, Aurélie, DiCioccio, A. Thomas, Cannon, Christopher P., Surks, Howard K., Pinquier, Jean‐Louis, Hanotin, Corinne, Sasiela, William J.

Journal:

Journal of the American Heart Association

Year:

2016

Language:

english

File:

PDF, 1.99 MB

english, 2016

12

Long-term treatment adherence to the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab in 6 ODYSSEY Phase III clinical studies with treatment duration of 1 to 2 years

Farnier, Michel, Colhoun, Helen M., Sasiela, William J., Edelberg, Jay M., Asset, Gaëlle, Robinson, Jennifer G.

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 1.03 MB

english, 2017

13

ALIROCUMAB REDUCES MAJOR CARDIOVASCULAR EVENTS IN INDIVIDUALS WITH ATHEROSCLEROTIC CARDIOVASCULAR DISEASE: A POST-HOC ANALYSIS OF ODYSSEY LONG TERM

Robinson, Jennifer, Farnier, Michel, Sasiela, William J., Nguyen, Tu, Mandel, Jonas, Kastelein, John

Journal:

Journal of the American College of Cardiology

Year:

2017

Language:

english

File:

PDF, 1.14 MB

english, 2017

14

1117-88 High-density lipoprotein, but not low-density lipoprotein cholesterol levels influence short-term prognosis after acute coronary syndrome: Results from the MIRACL trial

Anders G Olsson, Gregory G Schwartz, Michael D Ezekowitz, Peter Ganz, Michael F Oliver, David Waters, Andreas Zeiher, William Sasiela, Michael Szarek

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 95 KB

english, 2004

15

SPIE Proceedings [SPIE SPIE's International Symposium on Optical Engineering and Photonics in Aerospace Sensing - Orlando, FL (Monday 4 April 1994)] Sensing, Imaging, and Vision for Control and Guidance of Aerospace Vehicles - Target detection using radar images of an airport surface

Schultz, Hayden B., Wyschogrod, Daniel, Harman, William H., Sasiela, Richard J., Bush, Richard W., Verly, Jacques G., Welch, Sharon S.

Year:

1994

Language:

english

File:

PDF, 1.09 MB

english, 1994

16

Simulation of the Impact of Statin Intolerance on the Need for Ezetimibe and/or Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor for Meeting Low-Density Lipoprotein Cholesterol Goals in a Population With Atherosclerotic Cardiovascular Disease

Cannon, Christopher P., Sanchez, Robert J., Klimchak, Alexa C., Khan, Irfan, Sasiela, William J., Reynolds, Matthew R., Rosenson, Robert S.

Journal:

The American Journal of Cardiology

Year:

2019

Language:

english

File:

PDF, 1.56 MB

english, 2019

17

Factors that Influence Bempedoic Acid-Mediated Reductions in High-sensitivity C reactive Protein: Analysis of Pooled Patient-level Data from Phase 3 Clinical Trialsâ

Stroes, Erik, Bays, Harold, Banach, Maciej, Catapano, Alberico, Duell, P., Laufs, Ulrich, Mancini, G.B., Ray, Kausik, Sasiela, William, Ye, Zhan, Gotto, Antonio

Journal:

Journal of Clinical Lipidology

Year:

2020

File:

PDF, 88 KB

2020

18

Pharmacodynamic relationship between PCSK9, alirocumab, and LDL-C lowering in the ODYSSEY CHOICE I trial

Roth, Eli M., Kastelein, John J.P., Cannon, Christopher P., Farnier, Michel, McKenney, James M., DiCioccio, A. Thomas, Brunet, AurÃ©lie, Manvelian, Garen, Sasiela, William J., Baccara-Dinet, Marie T.,

Journal:

Journal of Clinical Lipidology

Year:

2020

File:

PDF, 2.65 MB

2020

19

Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia

Samaha, Frederick F, McKenney, James, Bloedon, LeAnne T, Sasiela, William J, Rader, Daniel J

Journal:

Nature Clinical Practice Cardiovascular Medicine

Year:

2008

Language:

english

File:

PDF, 249 KB

english, 2008

20

SPIE Proceedings [SPIE SPIE's International Symposium on Optical Engineering and Photonics in Aerospace Sensing - Orlando, FL (Monday 4 April 1994)] Sensing, Imaging, and Vision for Control and Guidance of Aerospace Vehicles - Connected components and temporal association in airport surface radar tracking

Wyschogrod, Daniel, Schultz, Hayden B., Harman, William H., Eggert, James R., Sasiela, Richard J., Bush, Richard W., Verly, Jacques G., Welch, Sharon S.

Year:

1994

Language:

english

File:

PDF, 1.44 MB

english, 1994

21

SPIE Proceedings [SPIE SPIE's International Symposium on Optical Engineering and Photonics in Aerospace Sensing - Orlando, FL (Monday 4 April 1994)] Sensing, Imaging, and Vision for Control and Guidance of Aerospace Vehicles - Radar images of Logan Airport and application in automated aircraft tracking

Harman, William H., Schultz, Hayden B., Wyschogrod, Daniel, Eggert, James R., Sasiela, Richard J., Bush, Richard W., Verly, Jacques G., Welch, Sharon S.

Year:

1994

Language:

english

File:

PDF, 759 KB

english, 1994

22

Statin Therapy, LDL Cholesterol, C-Reactive Protein, and Coronary Artery Disease

Nissen, Steven E., Tuzcu, E. Murat, Schoenhagen, Paul, Crowe, Tim, Sasiela, William J., Tsai, John, Orazem, John, Magorien, Raymond D., O'Shaughnessy, Charles, Ganz, Peter

Journal:

Boston Medical and Surgical Journal

Year:

2005

Language:

english

File:

PDF, 171 KB

english, 2005

23

Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia: a single-arm, open-label, proof-of-concept study

Gaudet, Daniel, Gipe, Daniel, Hovingh, Kees, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman, Chyu, Kuang -Yuh, Pordy, Robert, Sasiela, William, Chan, Kuo -Chen, Khoury, Etienne

Journal:

Atherosclerosis

Year:

2017

Language:

english

File:

PDF, 53 KB

english, 2017

24

Safety and Efficacy of Evinacumab, A Monoclonal Antibody to ANGPTL3, In Homozygous Familial Hypercholesterolemia

Gaudet, Daniel, Gipe, Daniel, Hovingh, Kees, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman, Chyu, Kuang-Yuh, Pordy, Robert, Sasiela, William, Chan, Kuo-Chen, Khoury, Etienne

Journal:

Journal of Clinical Lipidology

Year:

2017

Language:

english

File:

PDF, 217 KB

english, 2017

25

FACTORS THAT INFLUENCE BEMPEDOIC ACID-MEDIATED REDUCTIONS IN HIGH-SENSITIVITY C-REACTIVE PROTEIN: ANALYSIS OF POOLED PATIENT-LEVEL DATA FROM PHASE 3 CLINICAL TRIALS

Stroes, Erik S. G, Bays, Harold, Banach, Maciej, Catapano, Alberico, Duell, P. Barton, Laufs, Ulrich, Mancini, G.B. John, Ray, Kausik Kumar, Sasiela, William, Ye, Zhan, Gotto, Antonio M.

Journal:

Journal of the American College of Cardiology

Year:

2020

File:

PDF, 215 KB

2020

26

1084-173 Analysis of the renal safety of atorvastatin in a broad spectrum of patients with dyslipidemia

William Sasiela, Halit Silbershatz, Michael Szarek

Journal:

Journal of the American College of Cardiology

Year:

2004

Language:

english

File:

PDF, 88 KB

english, 2004

27

Effect of Alirocumab on Lipoprotein(a) Over ≥1.5 Years (From the Phase 3 ODYSSEY Program)

Gaudet, Daniel, Watts, Gerald F., Robinson, Jennifer G., Minini, Pascal, Sasiela, William J., Edelberg, Jay, Louie, Michael J., Raal, Frederick J.

Journal:

The American Journal of Cardiology

Year:

2016

Language:

english

File:

PDF, 483 KB

english, 2016

28

Simulation of impact on cardiovascular events due to lipid-lowering therapy intensification in a population with atherosclerotic cardiovascular disease

Cannon, Christopher P., Khan, Irfan, Klimchak, Alexa C., Sanchez, Robert J., Sasiela, William J., Massaro, Joseph M., D'Agostino, Ralph B., Reynolds, Matthew R.

Journal:

American Heart Journal

Year:

2019

Language:

english

File:

PDF, 1.61 MB

english, 2019

29

Safety and efficacy of evinacumab, a monoclonal antibody to ANGPTL3, in patients with homozygous familial hypercholesterolemia receiving concomitant lipid-lowering therapies

Gaudet, Daniel, Gipe, Daniel A., Pordy, Robert, Sasiela, William, Chan, Kuo-Chen, Khoury, Etienne

Journal:

Journal of Clinical Lipidology

Year:

2016

Language:

english

File:

PDF, 43 KB

english, 2016

30

An examination of atorvastatin safety when used in c combination with verapamil: Evidence from 44 completed clinical trials

William J. Sasiela, Michael Szarek, Halit Silbershatz, Gary Palmer

Journal:

Journal of the American College of Cardiology

Year:

2003

Language:

english

File:

PDF, 168 KB

english, 2003

31

ANGPTL3 Inhibition in Homozygous Familial Hypercholesterolemia

Gaudet, Daniel, Gipe, Daniel A., Pordy, Robert, Ahmad, Zahid, Cuchel, Marina, Shah, Prediman K., Chyu, Kuang-Yuh, Sasiela, William J., Chan, Kuo-Chen, Brisson, Diane, Khoury, Etienne, Banerjee, Poulab

Journal:

New England Journal of Medicine

Year:

2017

Language:

english

File:

PDF, 73 KB

english, 2017

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